BDBM50339461 3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid::CHEMBL1688458

SMILES: OC(=O)CCc1ccc(OCc2cccc(Oc3ccccc3)c2)cc1

InChI Key: InChIKey=BWNUDKFBKGPSBH-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50339461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50339461 (3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid |...) Show SMILES OC(=O)CCc1ccc(OCc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C22H20O4/c23-22(24)14-11-17-9-12-19(13-10-17)25-16-18-5-4-8-21(15-18)26-20-6-2-1-3-7-20/h1-10,12-13,15H,11,14,16H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Agonist activity against human GPR40 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPR assay in presence of 0.1% BS...				J Med Chem 54: 1365-78 (2011) Article DOI: 10.1021/jm101405t BindingDB Entry DOI: 10.7270/Q2251JG7
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50339461 (3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid |...) Show SMILES OC(=O)CCc1ccc(OCc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C22H20O4/c23-22(24)14-11-17-9-12-19(13-10-17)25-16-18-5-4-8-21(15-18)26-20-6-2-1-3-7-20/h1-10,12-13,15H,11,14,16H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	63.1	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at FFAR1 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 30 mins by BRET assay				J Med Chem 55: 4511-5 (2012) Article DOI: 10.1021/jm300215x BindingDB Entry DOI: 10.7270/Q21Z45P4
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50339461 (3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid |...) Show SMILES OC(=O)CCc1ccc(OCc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C22H20O4/c23-22(24)14-11-17-9-12-19(13-10-17)25-16-18-5-4-8-21(15-18)26-20-6-2-1-3-7-20/h1-10,12-13,15H,11,14,16H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human FFA1 receptor expressed in human U2OS cells co-expressing Galpha16 assessed as calcium mobilization by Fluo-4 dye based FLI...				Bioorg Med Chem Lett 27: 1278-1283 (2017) BindingDB Entry DOI: 10.7270/Q2ZK5JWB
					More data for this Ligand-Target Pair
G-protein coupled receptor 120 (Homo sapiens (Human))	BDBM50339461 (3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid |...) Show SMILES OC(=O)CCc1ccc(OCc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C22H20O4/c23-22(24)14-11-17-9-12-19(13-10-17)25-16-18-5-4-8-21(15-18)26-20-6-2-1-3-7-20/h1-10,12-13,15H,11,14,16H2,(H,23,24)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	968	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human FFA4 receptor expressed in human U2OS cells co-expressing Galpha16 assessed as calcium mobilization by Fluo-4 dye based FLI...				Bioorg Med Chem Lett 27: 1278-1283 (2017) BindingDB Entry DOI: 10.7270/Q2ZK5JWB
					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50339461 (3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid |...) Show SMILES OC(=O)CCc1ccc(OCc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C22H20O4/c23-22(24)14-11-17-9-12-19(13-10-17)25-16-18-5-4-8-21(15-18)26-20-6-2-1-3-7-20/h1-10,12-13,15H,11,14,16H2,(H,23,24)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	562	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at GPR120 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 5 mins by BRET assay				J Med Chem 55: 4511-5 (2012) Article DOI: 10.1021/jm300215x BindingDB Entry DOI: 10.7270/Q21Z45P4
					More data for this Ligand-Target Pair