BDBM50339626 1-(Benzo[d][1,3]dioxole-6-carbonyl)-3-(3-chloro-4-hydroxyphenyl)urea::CHEMBL1688877

SMILES: Oc1ccc(NC(=O)NC(=O)c2ccc3OCOc3c2)cc1Cl

InChI Key: InChIKey=FKXFNKGMURVCLI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50339626 (1-(Benzo[d][1,3]dioxole-6-carbonyl)-3-(3-chloro-4-...) Show SMILES Oc1ccc(NC(=O)NC(=O)c2ccc3OCOc3c2)cc1Cl Show InChI InChI=1S/C15H11ClN2O5/c16-10-6-9(2-3-11(10)19)17-15(21)18-14(20)8-1-4-12-13(5-8)23-7-22-12/h1-6,19H,7H2,(H2,17,18,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Telik, Inc. Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of CCL2-induced chemotaxis				J Med Chem 54: 1667-81 (2011) Article DOI: 10.1021/jm1012903 BindingDB Entry DOI: 10.7270/Q28K79DQ
					More data for this Ligand-Target Pair