BDBM50339633 1-(Benzo[d][1,3]dioxole-6-carbonyl)-3-(3-chlorophenyl)-1-methylurea::CHEMBL1688883

SMILES: CN(C(=O)Nc1cccc(Cl)c1)C(=O)c1ccc2OCOc2c1

InChI Key: InChIKey=IZAUMBYPBQPFPK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50339633 (1-(Benzo[d][1,3]dioxole-6-carbonyl)-3-(3-chlorophe...) Show SMILES CN(C(=O)Nc1cccc(Cl)c1)C(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C16H13ClN2O4/c1-19(16(21)18-12-4-2-3-11(17)8-12)15(20)10-5-6-13-14(7-10)23-9-22-13/h2-8H,9H2,1H3,(H,18,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Telik, Inc. Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of CCL2-induced chemotaxis				J Med Chem 54: 1667-81 (2011) Article DOI: 10.1021/jm1012903 BindingDB Entry DOI: 10.7270/Q28K79DQ
					More data for this Ligand-Target Pair