BDBM50339745 CHEMBL1689045::rac-2-Benzyl-N-[1-ethyl-1-(4-methylphenyl)propyl]-7,7-dimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]-pyrimidine-3-carboxamide hydrochloride

SMILES: CCC(CC)(NC(=O)c1c(Cc2ccccc2)nn2c1NC(CC2(C)C)c1ccccc1)c1ccc(C)cc1

InChI Key: InChIKey=MCBLXDKDGRRYOX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50339745 (CHEMBL1689045 | rac-2-Benzyl-N-[1-ethyl-1-(4-methy...) Show SMILES CCC(CC)(NC(=O)c1c(Cc2ccccc2)nn2c1NC(CC2(C)C)c1ccccc1)c1ccc(C)cc1 Show InChI InChI=1S/C34H40N4O/c1-6-34(7-2,27-20-18-24(3)19-21-27)36-32(39)30-28(22-25-14-10-8-11-15-25)37-38-31(30)35-29(23-33(38,4)5)26-16-12-9-13-17-26/h8-21,29,35H,6-7,22-23H2,1-5H3,(H,36,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Antagonist activity at CaSR expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding after 10 mins by scintillation counting				Bioorg Med Chem 19: 1881-94 (2011) Article DOI: 10.1016/j.bmc.2011.02.001 BindingDB Entry DOI: 10.7270/Q2MW2HFZ
					More data for this Ligand-Target Pair