BDBM50339876 6-bromo-N-(2-fluorophenyl)-4H-spiro[benzo[d][1,3]dioxine-2,4'-piperidine]-1'-carboxamide::CHEMBL1761279

SMILES: Fc1ccccc1NC(=O)N1CCC2(CC1)OCc1cc(Br)ccc1O2

InChI Key: InChIKey=DCIPWBDOWNKCCS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50339876 (6-bromo-N-(2-fluorophenyl)-4H-spiro[benzo[d][1,3]d...) Show SMILES Fc1ccccc1NC(=O)N1CCC2(CC1)OCc1cc(Br)ccc1O2 Show InChI InChI=1S/C19H18BrFN2O3/c20-14-5-6-17-13(11-14)12-25-19(26-17)7-9-23(10-8-19)18(24)22-16-4-2-1-3-15(16)21/h1-6,11H,7-10,12H2,(H,22,24)	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarin				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50339876 (6-bromo-N-(2-fluorophenyl)-4H-spiro[benzo[d][1,3]d...) Show SMILES Fc1ccccc1NC(=O)N1CCC2(CC1)OCc1cc(Br)ccc1O2 Show InChI InChI=1S/C19H18BrFN2O3/c20-14-5-6-17-13(11-14)12-25-19(26-17)7-9-23(10-8-19)18(24)22-16-4-2-1-3-15(16)21/h1-6,11H,7-10,12H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarin				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair