BDBM50339881 2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)piperidin-3-yl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetonitrile::CHEMBL1761306

SMILES: N#CCn1cc(C2CCCN(C2)c2nccc(n2)-c2cc3ccccc3s2)c2cccnc12

InChI Key: InChIKey=UGDFHKDERAZDTE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50339881 (2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)p...) Show SMILES N#CCn1cc(C2CCCN(C2)c2nccc(n2)-c2cc3ccccc3s2)c2cccnc12 Show InChI InChI=1S/C26H22N6S/c27-10-14-31-17-21(20-7-3-11-28-25(20)31)19-6-4-13-32(16-19)26-29-12-9-22(30-26)24-15-18-5-1-2-8-23(18)33-24/h1-3,5,7-9,11-12,15,17,19H,4,6,13-14,16H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarin				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50339881 (2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)p...) Show SMILES N#CCn1cc(C2CCCN(C2)c2nccc(n2)-c2cc3ccccc3s2)c2cccnc12 Show InChI InChI=1S/C26H22N6S/c27-10-14-31-17-21(20-7-3-11-28-25(20)31)19-6-4-13-32(16-19)26-29-12-9-22(30-26)24-15-18-5-1-2-8-23(18)33-24/h1-3,5,7-9,11-12,15,17,19H,4,6,13-14,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarin				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair