BDBM50339882 (S)-3-(1-(2-amino-6-(benzofuran-2-yl)pyrimidin-4-yl)piperidin-3-yl)-1-ethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one::CHEMBL1761291

SMILES: CCn1c2cccnc2n([C@H]2CCCN(C2)c2cc(nc(N)n2)-c2cc3ccccc3o2)c1=O

InChI Key: InChIKey=QFXIPDZEIKQHCZ-KRWDZBQOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339882   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50339882 ((S)-3-(1-(2-amino-6-(benzofuran-2-yl)pyrimidin-4-y...) Show SMILES CCn1c2cccnc2n([C@H]2CCCN(C2)c2cc(nc(N)n2)-c2cc3ccccc3o2)c1=O |r| Show InChI InChI=1S/C25H25N7O2/c1-2-31-19-9-5-11-27-23(19)32(25(31)33)17-8-6-12-30(15-17)22-14-18(28-24(26)29-22)21-13-16-7-3-4-10-20(16)34-21/h3-5,7,9-11,13-14,17H,2,6,8,12,15H2,1H3,(H2,26,28,29)/t17-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarin				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50339882 ((S)-3-(1-(2-amino-6-(benzofuran-2-yl)pyrimidin-4-y...) Show SMILES CCn1c2cccnc2n([C@H]2CCCN(C2)c2cc(nc(N)n2)-c2cc3ccccc3o2)c1=O |r| Show InChI InChI=1S/C25H25N7O2/c1-2-31-19-9-5-11-27-23(19)32(25(31)33)17-8-6-12-30(15-17)22-14-18(28-24(26)29-22)21-13-16-7-3-4-10-20(16)34-21/h3-5,7,9-11,13-14,17H,2,6,8,12,15H2,1H3,(H2,26,28,29)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarin				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair