BDBM50339889 (S)-1-(1-(2-(benzofuran-2-yl)pyrimidin-4-yl)piperidin-3-yl)-3-ethyl-1H-benzo[d]imidazol-2(3H)-one::CHEMBL1761289

SMILES: CCn1c2ccccc2n([C@H]2CCCN(C2)c2ccnc(n2)-c2cc3ccccc3o2)c1=O

InChI Key: InChIKey=HNAXTPUAJURCOW-IBGZPJMESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50339889 ((S)-1-(1-(2-(benzofuran-2-yl)pyrimidin-4-yl)piperi...) Show SMILES CCn1c2ccccc2n([C@H]2CCCN(C2)c2ccnc(n2)-c2cc3ccccc3o2)c1=O |r| Show InChI InChI=1S/C26H25N5O2/c1-2-30-20-10-4-5-11-21(20)31(26(30)32)19-9-7-15-29(17-19)24-13-14-27-25(28-24)23-16-18-8-3-6-12-22(18)33-23/h3-6,8,10-14,16,19H,2,7,9,15,17H2,1H3/t19-/m0/s1	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarin				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50339889 ((S)-1-(1-(2-(benzofuran-2-yl)pyrimidin-4-yl)piperi...) Show SMILES CCn1c2ccccc2n([C@H]2CCCN(C2)c2ccnc(n2)-c2cc3ccccc3o2)c1=O |r| Show InChI InChI=1S/C26H25N5O2/c1-2-30-20-10-4-5-11-21(20)31(26(30)32)19-9-7-15-29(17-19)24-13-14-27-25(28-24)23-16-18-8-3-6-12-22(18)33-23/h3-6,8,10-14,16,19H,2,7,9,15,17H2,1H3/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarin				Bioorg Med Chem Lett 21: 2492-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.052 BindingDB Entry DOI: 10.7270/Q2BG2P9M
					More data for this Ligand-Target Pair