BDBM50340120 CHEMBL1760034::N2-(naphthalen-2-yl)-N4-(3,4,5-trimethoxyphenyl)-1,3,5-triazine-2,4-diamine

SMILES: COc1cc(Nc2ncnc(Nc3ccc4ccccc4c3)n2)cc(OC)c1OC

InChI Key: InChIKey=QLHPKTYPPJIUFR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340120   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50340120 (CHEMBL1760034 | N2-(naphthalen-2-yl)-N4-(3,4,5-tri...) Show SMILES COc1cc(Nc2ncnc(Nc3ccc4ccccc4c3)n2)cc(OC)c1OC Show InChI InChI=1S/C22H21N5O3/c1-28-18-11-17(12-19(29-2)20(18)30-3)26-22-24-13-23-21(27-22)25-16-9-8-14-6-4-5-7-15(14)10-16/h4-13H,1-3H3,(H2,23,24,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	409	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hr				Bioorg Med Chem Lett 21: 2394-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.075 BindingDB Entry DOI: 10.7270/Q28G8M0D
					More data for this Ligand-Target Pair
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50340120 (CHEMBL1760034 | N2-(naphthalen-2-yl)-N4-(3,4,5-tri...) Show SMILES COc1cc(Nc2ncnc(Nc3ccc4ccccc4c3)n2)cc(OC)c1OC Show InChI InChI=1S/C22H21N5O3/c1-28-18-11-17(12-19(29-2)20(18)30-3)26-22-24-13-23-21(27-22)25-16-9-8-14-6-4-5-7-15(14)10-16/h4-13H,1-3H3,(H2,23,24,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human IGF1R				Bioorg Med Chem Lett 21: 2394-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.075 BindingDB Entry DOI: 10.7270/Q28G8M0D
					More data for this Ligand-Target Pair