BDBM50340255 CHEMBL1760607

SMILES: Cc1c2CCNCCOCCNc3cc(ccc3C(N)=O)-n2c2CC(C)(C)CC(=O)c12

InChI Key: InChIKey=LHSUFRLOYYYVOY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM50340255 (CHEMBL1760607) Show SMILES Cc1c2CCNCCOCCNc3cc(ccc3C(N)=O)-n2c2CC(C)(C)CC(=O)c12 Show InChI InChI=1S/C24H32N4O3/c1-15-19-6-7-26-8-10-31-11-9-27-18-12-16(4-5-17(18)23(25)30)28(19)20-13-24(2,3)14-21(29)22(15)20/h4-5,12,26-27H,6-11,13-14H2,1-3H3,(H2,25,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assay				Bioorg Med Chem Lett 21: 2278-82 (2011) Article DOI: 10.1016/j.bmcl.2011.02.101 BindingDB Entry DOI: 10.7270/Q2RF5VBN
					More data for this Ligand-Target Pair