BindingDB logo
myBDB logout

null

SMILES: COc1cc(C)c(Cl)cc1NC(=O)NCCc1ccc2nc(NC(C)=O)[nH]c2c1

InChI Key: InChIKey=WCJPFQNQMCJLJC-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340277   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAF proto-oncogene serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50340277
PNG
(CHEMBL1760637 | N-(6-(2-(3-(5-chloro-2-methoxy-4-m...)
Show SMILES COc1cc(C)c(Cl)cc1NC(=O)NCCc1ccc2nc(NC(C)=O)[nH]c2c1
Show InChI InChI=1S/C20H22ClN5O3/c1-11-8-18(29-3)17(10-14(11)21)26-20(28)22-7-6-13-4-5-15-16(9-13)25-19(24-15)23-12(2)27/h4-5,8-10H,6-7H2,1-3H3,(H2,22,26,28)(H2,23,24,25,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 190n/an/an/an/an/an/a



Merck Serono

Curated by ChEMBL


Assay Description
Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting

Bioorg Med Chem Lett 21: 2264-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.108
BindingDB Entry DOI: 10.7270/Q2MS3T23
More data for this
Ligand-Target Pair