BDBM50340278 CHEMBL1760638::N-(6-(2-(3-(4-chloro-2-methoxy-5-methylphenyl)ureido)ethyl)-1H-benzo[d]imidazol-2-yl)acetamide

SMILES: COc1cc(Cl)c(C)cc1NC(=O)NCCc1ccc2nc(NC(C)=O)[nH]c2c1

InChI Key: InChIKey=KRRNMNNNGYTFTD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340278 (CHEMBL1760638 | N-(6-(2-(3-(4-chloro-2-methoxy-5-m...) Show SMILES COc1cc(Cl)c(C)cc1NC(=O)NCCc1ccc2nc(NC(C)=O)[nH]c2c1 Show InChI InChI=1S/C20H22ClN5O3/c1-11-8-17(18(29-3)10-14(11)21)26-20(28)22-7-6-13-4-5-15-16(9-13)25-19(24-15)23-12(2)27/h4-5,8-10H,6-7H2,1-3H3,(H2,22,26,28)(H2,23,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting				Bioorg Med Chem Lett 21: 2264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.108 BindingDB Entry DOI: 10.7270/Q2MS3T23
					More data for this Ligand-Target Pair