BDBM50340281 CHEMBL1760641::N-(6-(2-(3-(2-(2-(methylamino)ethoxy)-5-(trifluoromethyl)phenyl)ureido)ethyl)-1H-benzo[d]imidazol-2-yl)acetamide

SMILES: CNCCOc1ccc(cc1NC(=O)NCCc1ccc2nc(NC(C)=O)[nH]c2c1)C(F)(F)F

InChI Key: InChIKey=WVNJAJZDJSJLER-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340281 (CHEMBL1760641 | N-(6-(2-(3-(2-(2-(methylamino)etho...) Show SMILES CNCCOc1ccc(cc1NC(=O)NCCc1ccc2nc(NC(C)=O)[nH]c2c1)C(F)(F)F Show InChI InChI=1S/C22H25F3N6O3/c1-13(32)28-20-29-16-5-3-14(11-17(16)30-20)7-8-27-21(33)31-18-12-15(22(23,24)25)4-6-19(18)34-10-9-26-2/h3-6,11-12,26H,7-10H2,1-2H3,(H2,27,31,33)(H2,28,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting				Bioorg Med Chem Lett 21: 2264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.108 BindingDB Entry DOI: 10.7270/Q2MS3T23
					More data for this Ligand-Target Pair