BDBM50340609 8-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H-1,2,4-triazol-1-yl)phenyl)quinazolin-2-amine::CHEMBL1761564

SMILES: Cn1cc(cn1)-c1cccc2cnc(Nc3ccc(cc3)-n3cnc(n3)N3CCOCC3)nc12

InChI Key: InChIKey=MMCVYWQYORICCQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50340609 (8-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H...) Show SMILES Cn1cc(cn1)-c1cccc2cnc(Nc3ccc(cc3)-n3cnc(n3)N3CCOCC3)nc12 Show InChI InChI=1S/C24H23N9O/c1-31-15-18(14-27-31)21-4-2-3-17-13-25-23(29-22(17)21)28-19-5-7-20(8-6-19)33-16-26-24(30-33)32-9-11-34-12-10-32/h2-8,13-16H,9-12H2,1H3,(H,25,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3 by HRTF				Bioorg Med Chem Lett 21: 1719-23 (2011) Article DOI: 10.1016/j.bmcl.2011.01.079 BindingDB Entry DOI: 10.7270/Q2F1901V
					More data for this Ligand-Target Pair
Transcription factor Jun (Homo sapiens (Human))	BDBM50340609 (8-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H...) Show SMILES Cn1cc(cn1)-c1cccc2cnc(Nc3ccc(cc3)-n3cnc(n3)N3CCOCC3)nc12 Show InChI InChI=1S/C24H23N9O/c1-31-15-18(14-27-31)21-4-2-3-17-13-25-23(29-22(17)21)28-19-5-7-20(8-6-19)33-16-26-24(30-33)32-9-11-34-12-10-32/h2-8,13-16H,9-12H2,1H3,(H,25,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of c-Jun				Bioorg Med Chem Lett 21: 1719-23 (2011) Article DOI: 10.1016/j.bmcl.2011.01.079 BindingDB Entry DOI: 10.7270/Q2F1901V
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50340609 (8-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H...) Show SMILES Cn1cc(cn1)-c1cccc2cnc(Nc3ccc(cc3)-n3cnc(n3)N3CCOCC3)nc12 Show InChI InChI=1S/C24H23N9O/c1-31-15-18(14-27-31)21-4-2-3-17-13-25-23(29-22(17)21)28-19-5-7-20(8-6-19)33-16-26-24(30-33)32-9-11-34-12-10-32/h2-8,13-16H,9-12H2,1H3,(H,25,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 by HRTF				Bioorg Med Chem Lett 21: 1719-23 (2011) Article DOI: 10.1016/j.bmcl.2011.01.079 BindingDB Entry DOI: 10.7270/Q2F1901V
					More data for this Ligand-Target Pair