null

SMILES: Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCCNCc4ccc(OCc5ccccc5C(=O)Nc5ccc6nc(C)cc(N)c6c5)cc4)cc3)ccc2n1

InChI Key: InChIKey=RLIBKISXFVIFNR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340687   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50340687 (CHEMBL1762383 | N,N'-bis[[4-[[2-[[(4-amino-2-methy...) Show SMILES Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCCNCc4ccc(OCc5ccccc5C(=O)Nc5ccc6nc(C)cc(N)c6c5)cc4)cc3)ccc2n1 Show InChI InChI=1S/C55H56N8O4/c1-36-28-50(56)48-30-42(18-24-52(48)60-36)62-54(64)46-12-6-4-10-40(46)34-66-44-20-14-38(15-21-44)32-58-26-8-3-9-27-59-33-39-16-22-45(23-17-39)67-35-41-11-5-7-13-47(41)55(65)63-43-19-25-53-49(31-43)51(57)29-37(2)61-53/h4-7,10-25,28-31,58-59H,3,8-9,26-27,32-35H2,1-2H3,(H2,56,60)(H2,57,61)(H,62,64)(H,63,65)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [3H]-naltrindole from human kappa opioid receptor expressed in human HEK293 cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50340687 (CHEMBL1762383 | N,N'-bis[[4-[[2-[[(4-amino-2-methy...) Show SMILES Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCCNCc4ccc(OCc5ccccc5C(=O)Nc5ccc6nc(C)cc(N)c6c5)cc4)cc3)ccc2n1 Show InChI InChI=1S/C55H56N8O4/c1-36-28-50(56)48-30-42(18-24-52(48)60-36)62-54(64)46-12-6-4-10-40(46)34-66-44-20-14-38(15-21-44)32-58-26-8-3-9-27-59-33-39-16-22-45(23-17-39)67-35-41-11-5-7-13-47(41)55(65)63-43-19-25-53-49(31-43)51(57)29-37(2)61-53/h4-7,10-25,28-31,58-59H,3,8-9,26-27,32-35H2,1-2H3,(H2,56,60)(H2,57,61)(H,62,64)(H,63,65)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76.2	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-nociceptin from human NOP receptor expressed in human HEK293 cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50340687 (CHEMBL1762383 | N,N'-bis[[4-[[2-[[(4-amino-2-methy...) Show SMILES Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCCNCc4ccc(OCc5ccccc5C(=O)Nc5ccc6nc(C)cc(N)c6c5)cc4)cc3)ccc2n1 Show InChI InChI=1S/C55H56N8O4/c1-36-28-50(56)48-30-42(18-24-52(48)60-36)62-54(64)46-12-6-4-10-40(46)34-66-44-20-14-38(15-21-44)32-58-26-8-3-9-27-59-33-39-16-22-45(23-17-39)67-35-41-11-5-7-13-47(41)55(65)63-43-19-25-53-49(31-43)51(57)29-37(2)61-53/h4-7,10-25,28-31,58-59H,3,8-9,26-27,32-35H2,1-2H3,(H2,56,60)(H2,57,61)(H,62,64)(H,63,65)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [3H]-naltrindole from human mu opioid receptor expressed in CHO cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair