null

SMILES: Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCCCCCCCNCc4ccc(OCc5ccccc5C(=O)Nc5ccc6nc(C)cc(N)c6c5)cc4)cc3)ccc2n1

InChI Key: InChIKey=ODMUFWVINBBREW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50340692 (CHEMBL1762388 | N,N'-bis[[4-[[2-[[(4-amino-2-methy...) Show SMILES Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCCCCCCCNCc4ccc(OCc5ccccc5C(=O)Nc5ccc6nc(C)cc(N)c6c5)cc4)cc3)ccc2n1 Show InChI InChI=1S/C60H66N8O4/c1-41-33-55(61)53-35-47(23-29-57(53)65-41)67-59(69)51-17-11-9-15-45(51)39-71-49-25-19-43(20-26-49)37-63-31-13-7-5-3-4-6-8-14-32-64-38-44-21-27-50(28-22-44)72-40-46-16-10-12-18-52(46)60(70)68-48-24-30-58-54(36-48)56(62)34-42(2)66-58/h9-12,15-30,33-36,63-64H,3-8,13-14,31-32,37-40H2,1-2H3,(H2,61,65)(H2,62,66)(H,67,69)(H,68,70)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [3H]-naltrindole from human kappa opioid receptor expressed in human HEK293 cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50340692 (CHEMBL1762388 | N,N'-bis[[4-[[2-[[(4-amino-2-methy...) Show SMILES Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCCCCCCCNCc4ccc(OCc5ccccc5C(=O)Nc5ccc6nc(C)cc(N)c6c5)cc4)cc3)ccc2n1 Show InChI InChI=1S/C60H66N8O4/c1-41-33-55(61)53-35-47(23-29-57(53)65-41)67-59(69)51-17-11-9-15-45(51)39-71-49-25-19-43(20-26-49)37-63-31-13-7-5-3-4-6-8-14-32-64-38-44-21-27-50(28-22-44)72-40-46-16-10-12-18-52(46)60(70)68-48-24-30-58-54(36-48)56(62)34-42(2)66-58/h9-12,15-30,33-36,63-64H,3-8,13-14,31-32,37-40H2,1-2H3,(H2,61,65)(H2,62,66)(H,67,69)(H,68,70)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32.7	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-nociceptin from human NOP receptor expressed in human HEK293 cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50340692 (CHEMBL1762388 | N,N'-bis[[4-[[2-[[(4-amino-2-methy...) Show SMILES Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCCCCCCCNCc4ccc(OCc5ccccc5C(=O)Nc5ccc6nc(C)cc(N)c6c5)cc4)cc3)ccc2n1 Show InChI InChI=1S/C60H66N8O4/c1-41-33-55(61)53-35-47(23-29-57(53)65-41)67-59(69)51-17-11-9-15-45(51)39-71-49-25-19-43(20-26-49)37-63-31-13-7-5-3-4-6-8-14-32-64-38-44-21-27-50(28-22-44)72-40-46-16-10-12-18-52(46)60(70)68-48-24-30-58-54(36-48)56(62)34-42(2)66-58/h9-12,15-30,33-36,63-64H,3-8,13-14,31-32,37-40H2,1-2H3,(H2,61,65)(H2,62,66)(H,67,69)(H,68,70)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [3H]-naltrindole from human mu opioid receptor expressed in CHO cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair