BDBM50340700 CHEMBL1762404::N-(4-amino-2-methylquinolin-6-yl)-2-[4-(decylaminomethyl)phenoxymethyl]benzamide

SMILES: CCCCCCCCCCNCc1ccc(OCc2ccccc2C(=O)Nc2ccc3nc(C)cc(N)c3c2)cc1

InChI Key: InChIKey=NISPVHKSBITFCL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340700   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50340700 (CHEMBL1762404 | N-(4-amino-2-methylquinolin-6-yl)-...) Show SMILES CCCCCCCCCCNCc1ccc(OCc2ccccc2C(=O)Nc2ccc3nc(C)cc(N)c3c2)cc1 Show InChI InChI=1S/C35H44N4O2/c1-3-4-5-6-7-8-9-12-21-37-24-27-15-18-30(19-16-27)41-25-28-13-10-11-14-31(28)35(40)39-29-17-20-34-32(23-29)33(36)22-26(2)38-34/h10-11,13-20,22-23,37H,3-9,12,21,24-25H2,1-2H3,(H2,36,38)(H,39,40)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [3H]-naltrindole from human kappa opioid receptor expressed in human HEK293 cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50340700 (CHEMBL1762404 | N-(4-amino-2-methylquinolin-6-yl)-...) Show SMILES CCCCCCCCCCNCc1ccc(OCc2ccccc2C(=O)Nc2ccc3nc(C)cc(N)c3c2)cc1 Show InChI InChI=1S/C35H44N4O2/c1-3-4-5-6-7-8-9-12-21-37-24-27-15-18-30(19-16-27)41-25-28-13-10-11-14-31(28)35(40)39-29-17-20-34-32(23-29)33(36)22-26(2)38-34/h10-11,13-20,22-23,37H,3-9,12,21,24-25H2,1-2H3,(H2,36,38)(H,39,40)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [3H]-naltrindole from human mu opioid receptor expressed in CHO cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50340700 (CHEMBL1762404 | N-(4-amino-2-methylquinolin-6-yl)-...) Show SMILES CCCCCCCCCCNCc1ccc(OCc2ccccc2C(=O)Nc2ccc3nc(C)cc(N)c3c2)cc1 Show InChI InChI=1S/C35H44N4O2/c1-3-4-5-6-7-8-9-12-21-37-24-27-15-18-30(19-16-27)41-25-28-13-10-11-14-31(28)35(40)39-29-17-20-34-32(23-29)33(36)22-26(2)38-34/h10-11,13-20,22-23,37H,3-9,12,21,24-25H2,1-2H3,(H2,36,38)(H,39,40)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	405	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-nociceptin from human NOP receptor expressed in human HEK293 cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair