BDBM50340712 (E,E)-N,N'-bis[[4-[[2-[[(4-amino-2-methylquinolin-6-yl)amino]carbonyl]phenyl]methoxy]phenyl]methylene]-1,6-hexanediamine::CHEMBL1762376

SMILES: Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(\C=N\CCCCCC\N=C\c4ccc(OCc5ccccc5C(=O)Nc5ccc6nc(C)cc(N)c6c5)cc4)cc3)ccc2n1

InChI Key: InChIKey=IPVPCJVFYARXLY-UBLZWTTJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50340712 ((E,E)-N,N'-bis[[4-[[2-[[(4-amino-2-methylquinolin-...) Show SMILES Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(\C=N\CCCCCC\N=C\c4ccc(OCc5ccccc5C(=O)Nc5ccc6nc(C)cc(N)c6c5)cc4)cc3)ccc2n1 Show InChI InChI=1S/C56H54N8O4/c1-37-29-51(57)49-31-43(19-25-53(49)61-37)63-55(65)47-13-7-5-11-41(47)35-67-45-21-15-39(16-22-45)33-59-27-9-3-4-10-28-60-34-40-17-23-46(24-18-40)68-36-42-12-6-8-14-48(42)56(66)64-44-20-26-54-50(32-44)52(58)30-38(2)62-54/h5-8,11-26,29-34H,3-4,9-10,27-28,35-36H2,1-2H3,(H2,57,61)(H2,58,62)(H,63,65)(H,64,66)/b59-33+,60-34+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83.3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-nociceptin from human NOP receptor expressed in human HEK293 cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair