BDBM50340715 (E,E)-N,N'-bis[[4-[[2-[[(4-amino-2-methylquinolin-6-yl)amino]carbonyl]phenyl]methoxy]phenyl]methylene]-1,9-nonanediamine::CHEMBL1762379

SMILES: Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(\C=N\CCCCCCCCC\N=C\c4ccc(OCc5ccccc5C(=O)Nc5ccc6nc(C)cc(N)c6c5)cc4)cc3)ccc2n1

InChI Key: InChIKey=ZDMAUZHUTDDPRE-SJVHOBNKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50340715 ((E,E)-N,N'-bis[[4-[[2-[[(4-amino-2-methylquinolin-...) Show SMILES Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(\C=N\CCCCCCCCC\N=C\c4ccc(OCc5ccccc5C(=O)Nc5ccc6nc(C)cc(N)c6c5)cc4)cc3)ccc2n1 Show InChI InChI=1S/C59H60N8O4/c1-40-32-54(60)52-34-46(22-28-56(52)64-40)66-58(68)50-16-10-8-14-44(50)38-70-48-24-18-42(19-25-48)36-62-30-12-6-4-3-5-7-13-31-63-37-43-20-26-49(27-21-43)71-39-45-15-9-11-17-51(45)59(69)67-47-23-29-57-53(35-47)55(61)33-41(2)65-57/h8-11,14-29,32-37H,3-7,12-13,30-31,38-39H2,1-2H3,(H2,60,64)(H2,61,65)(H,66,68)(H,67,69)/b62-36+,63-37+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82.7	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-nociceptin from human NOP receptor expressed in human HEK293 cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair