BDBM50340717 (E)-N-(4-amino-2-methylquinolin-6-yl)-2-[4-(propyliminomethyl)phenoxymethyl]benzamide::CHEMBL1762389

SMILES: CCC\N=C\c1ccc(OCc2ccccc2C(=O)Nc2ccc3nc(C)cc(N)c3c2)cc1

InChI Key: InChIKey=VCNHSQRMETZNBA-OCSSWDANSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50340717 ((E)-N-(4-amino-2-methylquinolin-6-yl)-2-[4-(propyl...) Show SMILES CCC\N=C\c1ccc(OCc2ccccc2C(=O)Nc2ccc3nc(C)cc(N)c3c2)cc1 Show InChI InChI=1S/C28H28N4O2/c1-3-14-30-17-20-8-11-23(12-9-20)34-18-21-6-4-5-7-24(21)28(33)32-22-10-13-27-25(16-22)26(29)15-19(2)31-27/h4-13,15-17H,3,14,18H2,1-2H3,(H2,29,31)(H,32,33)/b30-17+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98.9	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-nociceptin from human NOP receptor expressed in human HEK293 cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair