BDBM50341156 3-(anthracen-9-yl)-5-phenyl-4,5-dihydro-1H-pyrazole::CHEMBL1760717
SMILES: C1C(N=NC1c1c2ccccc2cc2ccccc12)c1ccccc1
InChI Key: InChIKey=BQGQZXQTMPUOBR-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat)) | BDBM50341156 (3-(anthracen-9-yl)-5-phenyl-4,5-dihydro-1H-pyrazol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology Curated by ChEMBL | Assay Description Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry | Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50341156 (3-(anthracen-9-yl)-5-phenyl-4,5-dihydro-1H-pyrazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry | Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase (flavin-containing) A (Homo sapiens (Human)) | BDBM50341156 (3-(anthracen-9-yl)-5-phenyl-4,5-dihydro-1H-pyrazol...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 332 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant MAO-A after 60 mins using p-tyramine as substrate by spectrophotometry | Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoamine oxidase (Rattus norvegicus (rat)) | BDBM50341156 (3-(anthracen-9-yl)-5-phenyl-4,5-dihydro-1H-pyrazol...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 397 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology Curated by ChEMBL | Assay Description Competitive inhibition of rat liver MAO-A after 60 mins using p-tyramine as substrate by spectrophotometry | Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC | |||||||||||
More data for this Ligand-Target Pair |