BDBM50341494 CHEMBL1765464::N-(5-(3-(5-Methyl-1,2,4-oxadiazol-3-yl)imidazo[1,2-a]pyridin-6-yl)pyridin-3-yl)benzenesulfonamide

SMILES: Cc1nc(no1)-c1cnc2ccc(cn12)-c1cncc(NS(=O)(=O)c2ccccc2)c1

InChI Key: InChIKey=OLKGECFEMGIHJD-UHFFFAOYSA-N

Data: 1 IC50  4 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50341494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50341494 (CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...) Show SMILES Cc1nc(no1)-c1cnc2ccc(cn12)-c1cncc(NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C21H16N6O3S/c1-14-24-21(25-30-14)19-12-23-20-8-7-15(13-27(19)20)16-9-17(11-22-10-16)26-31(28,29)18-5-3-2-4-6-18/h2-13,26H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha after 180 mins by luminescent assay				J Med Chem 54: 2455-66 (2011) Article DOI: 10.1021/jm101582z BindingDB Entry DOI: 10.7270/Q2ZP46F1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 19 (Homo sapiens (Human))	BDBM50341494 (CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...) Show SMILES Cc1nc(no1)-c1cnc2ccc(cn12)-c1cncc(NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C21H16N6O3S/c1-14-24-21(25-30-14)19-12-23-20-8-7-15(13-27(19)20)16-9-17(11-22-10-16)26-31(28,29)18-5-3-2-4-6-18/h2-13,26H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology Curated by ChEMBL					Assay Description Binding affinity to CDK11 by high-throughput binding assay				J Med Chem 54: 2455-66 (2011) Article DOI: 10.1021/jm101582z BindingDB Entry DOI: 10.7270/Q2ZP46F1
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50341494 (CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...) Show SMILES Cc1nc(no1)-c1cnc2ccc(cn12)-c1cncc(NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C21H16N6O3S/c1-14-24-21(25-30-14)19-12-23-20-8-7-15(13-27(19)20)16-9-17(11-22-10-16)26-31(28,29)18-5-3-2-4-6-18/h2-13,26H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology Curated by ChEMBL					Assay Description Binding affinity to PIK3CB by high-throughput binding assay				J Med Chem 54: 2455-66 (2011) Article DOI: 10.1021/jm101582z BindingDB Entry DOI: 10.7270/Q2ZP46F1
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50341494 (CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...) Show SMILES Cc1nc(no1)-c1cnc2ccc(cn12)-c1cncc(NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C21H16N6O3S/c1-14-24-21(25-30-14)19-12-23-20-8-7-15(13-27(19)20)16-9-17(11-22-10-16)26-31(28,29)18-5-3-2-4-6-18/h2-13,26H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology Curated by ChEMBL					Assay Description Binding affinity to PIK3CA by high-throughput binding assay				J Med Chem 54: 2455-66 (2011) Article DOI: 10.1021/jm101582z BindingDB Entry DOI: 10.7270/Q2ZP46F1
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50341494 (CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...) Show SMILES Cc1nc(no1)-c1cnc2ccc(cn12)-c1cncc(NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C21H16N6O3S/c1-14-24-21(25-30-14)19-12-23-20-8-7-15(13-27(19)20)16-9-17(11-22-10-16)26-31(28,29)18-5-3-2-4-6-18/h2-13,26H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology Curated by ChEMBL					Assay Description Binding affinity to mTOR by high-throughput binding assay				J Med Chem 54: 2455-66 (2011) Article DOI: 10.1021/jm101582z BindingDB Entry DOI: 10.7270/Q2ZP46F1
					More data for this Ligand-Target Pair