BDBM50341538 3-(4-Ethylbenzoylamino)-5-(pyridin-4-yl)-(1H)-pyridin-2-one::CHEMBL1765768

SMILES: CCc1ccc(cc1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1

InChI Key: InChIKey=PDZVYFNEJNFOGW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341538   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50341538 (3-(4-Ethylbenzoylamino)-5-(pyridin-4-yl)-(1H)-pyri...) Show SMILES CCc1ccc(cc1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI InChI=1S/C19H17N3O2/c1-2-13-3-5-15(6-4-13)18(23)22-17-11-16(12-21-19(17)24)14-7-9-20-10-8-14/h3-12H,2H2,1H3,(H,21,24)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals (Europe) Ltd. Curated by ChEMBL					Assay Description Inhibition of Itk after 40 mins by radiometric phosphate incorporation assay				J Med Chem 54: 2341-50 (2011) Article DOI: 10.1021/jm101499u BindingDB Entry DOI: 10.7270/Q2KH0NPW
					More data for this Ligand-Target Pair