BDBM50341573 CHEMBL1766098::{4-[7-Chloro-3-(3,5-dimethylphenyl)-4-{2-[(2R)-piperidin-2-yl]ethoxy}quinolin-6-yl]phenyl}methanol

SMILES: Cc1cc(C)cc(c1)-c1cnc2cc(Cl)c(cc2c1OCC[C@H]1CCCCN1)-c1ccc(CO)cc1

InChI Key: InChIKey=OWRSMOOCLOGSNK-RUZDIDTESA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50341573 (CHEMBL1766098 | {4-[7-Chloro-3-(3,5-dimethylphenyl...) Show SMILES Cc1cc(C)cc(c1)-c1cnc2cc(Cl)c(cc2c1OCC[C@H]1CCCCN1)-c1ccc(CO)cc1 |r| Show InChI InChI=1S/C31H33ClN2O2/c1-20-13-21(2)15-24(14-20)28-18-34-30-17-29(32)26(23-8-6-22(19-35)7-9-23)16-27(30)31(28)36-12-10-25-5-3-4-11-33-25/h6-9,13-18,25,33,35H,3-5,10-12,19H2,1-2H3/t25-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of I125-somatostatin-14 from human SST2 expressed in CHO cells after 3 hrs by scintillation counting				J Med Chem 54: 2351-8 (2011) Article DOI: 10.1021/jm101501b BindingDB Entry DOI: 10.7270/Q2668DH8
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50341573 (CHEMBL1766098 | {4-[7-Chloro-3-(3,5-dimethylphenyl...) Show SMILES Cc1cc(C)cc(c1)-c1cnc2cc(Cl)c(cc2c1OCC[C@H]1CCCCN1)-c1ccc(CO)cc1 |r| Show InChI InChI=1S/C31H33ClN2O2/c1-20-13-21(2)15-24(14-20)28-18-34-30-17-29(32)26(23-8-6-22(19-35)7-9-23)16-27(30)31(28)36-12-10-25-5-3-4-11-33-25/h6-9,13-18,25,33,35H,3-5,10-12,19H2,1-2H3/t25-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human SST2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP release after 40 mins by luminescence assay				J Med Chem 54: 2351-8 (2011) Article DOI: 10.1021/jm101501b BindingDB Entry DOI: 10.7270/Q2668DH8
					More data for this Ligand-Target Pair