BDBM50341579 CHEMBL1766104::{3-[7-Chloro-6-(1-methyl-1H-pyrazol-4-yl)-4-{2-[(2R)-piperidin-2-yl]ethoxy}quinolin-3-yl]phenyl}methanol

SMILES: Cn1cc(cn1)-c1cc2c(OCC[C@H]3CCCCN3)c(cnc2cc1Cl)-c1cccc(CO)c1

InChI Key: InChIKey=VQEDLQGAGVLAFF-OAQYLSRUSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341579   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50341579 (CHEMBL1766104 | {3-[7-Chloro-6-(1-methyl-1H-pyrazo...) Show SMILES Cn1cc(cn1)-c1cc2c(OCC[C@H]3CCCCN3)c(cnc2cc1Cl)-c1cccc(CO)c1 |r| Show InChI InChI=1S/C27H29ClN4O2/c1-32-16-20(14-31-32)22-12-23-26(13-25(22)28)30-15-24(19-6-4-5-18(11-19)17-33)27(23)34-10-8-21-7-2-3-9-29-21/h4-6,11-16,21,29,33H,2-3,7-10,17H2,1H3/t21-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of I125-somatostatin-14 from human SST2 expressed in CHO cells after 3 hrs by scintillation counting				J Med Chem 54: 2351-8 (2011) Article DOI: 10.1021/jm101501b BindingDB Entry DOI: 10.7270/Q2668DH8
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50341579 (CHEMBL1766104 | {3-[7-Chloro-6-(1-methyl-1H-pyrazo...) Show SMILES Cn1cc(cn1)-c1cc2c(OCC[C@H]3CCCCN3)c(cnc2cc1Cl)-c1cccc(CO)c1 |r| Show InChI InChI=1S/C27H29ClN4O2/c1-32-16-20(14-31-32)22-12-23-26(13-25(22)28)30-15-24(19-6-4-5-18(11-19)17-33)27(23)34-10-8-21-7-2-3-9-29-21/h4-6,11-16,21,29,33H,2-3,7-10,17H2,1H3/t21-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human SST2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP release after 40 mins by luminescence assay				J Med Chem 54: 2351-8 (2011) Article DOI: 10.1021/jm101501b BindingDB Entry DOI: 10.7270/Q2668DH8
					More data for this Ligand-Target Pair