BDBM50341767 (1-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)-amino]pyridin-2-yl}azetidin-3-yloxy)acetic Acid::CHEMBL1766885

SMILES: OC(=O)COC1CN(C1)c1ccc(NC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2)cn1

InChI Key: InChIKey=GKXLACKKALNWDA-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50341767 ((1-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbon...) Show SMILES OC(=O)COC1CN(C1)c1ccc(NC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2)cn1 Show InChI InChI=1S/C21H17F3N4O5/c22-21(23,24)18-17(27-20(33-18)12-4-2-1-3-5-12)19(31)26-13-6-7-15(25-8-13)28-9-14(10-28)32-11-16(29)30/h1-8,14H,9-11H2,(H,26,31)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assay				J Med Chem 54: 2433-46 (2011) Article DOI: 10.1021/jm101580m BindingDB Entry DOI: 10.7270/Q2S182TQ
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50341767 ((1-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbon...) Show SMILES OC(=O)COC1CN(C1)c1ccc(NC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2)cn1 Show InChI InChI=1S/C21H17F3N4O5/c22-21(23,24)18-17(27-20(33-18)12-4-2-1-3-5-12)19(31)26-13-6-7-15(25-8-13)28-9-14(10-28)32-11-16(29)30/h1-8,14H,9-11H2,(H,26,31)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assay				J Med Chem 54: 2433-46 (2011) Article DOI: 10.1021/jm101580m BindingDB Entry DOI: 10.7270/Q2S182TQ
					More data for this Ligand-Target Pair