BDBM50341774 4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)-amino]phenyl}piperazine-1-carboxylic Acid Methyl Ester::CHEMBL1766893

SMILES: COC(=O)N1CCN(CC1)c1ccc(NC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2)cc1

InChI Key: InChIKey=REVVEZOXOUZNSG-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50341774 (4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...) Show SMILES COC(=O)N1CCN(CC1)c1ccc(NC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2)cc1 Show InChI InChI=1S/C23H21F3N4O4/c1-33-22(32)30-13-11-29(12-14-30)17-9-7-16(8-10-17)27-20(31)18-19(23(24,25)26)34-21(28-18)15-5-3-2-4-6-15/h2-10H,11-14H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assay				J Med Chem 54: 2433-46 (2011) Article DOI: 10.1021/jm101580m BindingDB Entry DOI: 10.7270/Q2S182TQ
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50341774 (4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...) Show SMILES COC(=O)N1CCN(CC1)c1ccc(NC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2)cc1 Show InChI InChI=1S/C23H21F3N4O4/c1-33-22(32)30-13-11-29(12-14-30)17-9-7-16(8-10-17)27-20(31)18-19(23(24,25)26)34-21(28-18)15-5-3-2-4-6-15/h2-10H,11-14H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assay				J Med Chem 54: 2433-46 (2011) Article DOI: 10.1021/jm101580m BindingDB Entry DOI: 10.7270/Q2S182TQ
					More data for this Ligand-Target Pair