BDBM50341852 3'-(8-(Hydroxyimino)-9-(methylamino)-9-oxononanamido)-[1,1'-biphenyl]-4-carboxylic Acid::CHEMBL1767037

SMILES: CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)=O)N=O

InChI Key: InChIKey=FXMFVAHFHJMAQP-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50341852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 5 (Homo sapiens (Human))	BDBM50341852 (3'-(8-(Hydroxyimino)-9-(methylamino)-9-oxononanami...) Show SMILES CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)=O)N=O Show InChI InChI=1S/C23H27N3O5/c1-24-22(28)20(26-31)9-4-2-3-5-10-21(27)25-19-8-6-7-18(15-19)16-11-13-17(14-12-16)23(29)30/h6-8,11-15,20H,2-5,9-10H2,1H3,(H,24,28)(H,25,27)(H,29,30)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC5 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assay				J Med Chem 54: 2165-82 (2011) Article DOI: 10.1021/jm101373a BindingDB Entry DOI: 10.7270/Q2CR5TNZ
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50341852 (3'-(8-(Hydroxyimino)-9-(methylamino)-9-oxononanami...) Show SMILES CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)=O)N=O Show InChI InChI=1S/C23H27N3O5/c1-24-22(28)20(26-31)9-4-2-3-5-10-21(27)25-19-8-6-7-18(15-19)16-11-13-17(14-12-16)23(29)30/h6-8,11-15,20H,2-5,9-10H2,1H3,(H,24,28)(H,25,27)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC1 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assay				J Med Chem 54: 2165-82 (2011) Article DOI: 10.1021/jm101373a BindingDB Entry DOI: 10.7270/Q2CR5TNZ
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50341852 (3'-(8-(Hydroxyimino)-9-(methylamino)-9-oxononanami...) Show SMILES CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)=O)N=O Show InChI InChI=1S/C23H27N3O5/c1-24-22(28)20(26-31)9-4-2-3-5-10-21(27)25-19-8-6-7-18(15-19)16-11-13-17(14-12-16)23(29)30/h6-8,11-15,20H,2-5,9-10H2,1H3,(H,24,28)(H,25,27)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC2 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assay				J Med Chem 54: 2165-82 (2011) Article DOI: 10.1021/jm101373a BindingDB Entry DOI: 10.7270/Q2CR5TNZ
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50341852 (3'-(8-(Hydroxyimino)-9-(methylamino)-9-oxononanami...) Show SMILES CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)=O)N=O Show InChI InChI=1S/C23H27N3O5/c1-24-22(28)20(26-31)9-4-2-3-5-10-21(27)25-19-8-6-7-18(15-19)16-11-13-17(14-12-16)23(29)30/h6-8,11-15,20H,2-5,9-10H2,1H3,(H,24,28)(H,25,27)(H,29,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC3 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assay				J Med Chem 54: 2165-82 (2011) Article DOI: 10.1021/jm101373a BindingDB Entry DOI: 10.7270/Q2CR5TNZ
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50341852 (3'-(8-(Hydroxyimino)-9-(methylamino)-9-oxononanami...) Show SMILES CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)=O)N=O Show InChI InChI=1S/C23H27N3O5/c1-24-22(28)20(26-31)9-4-2-3-5-10-21(27)25-19-8-6-7-18(15-19)16-11-13-17(14-12-16)23(29)30/h6-8,11-15,20H,2-5,9-10H2,1H3,(H,24,28)(H,25,27)(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC4 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assay				J Med Chem 54: 2165-82 (2011) Article DOI: 10.1021/jm101373a BindingDB Entry DOI: 10.7270/Q2CR5TNZ
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50341852 (3'-(8-(Hydroxyimino)-9-(methylamino)-9-oxononanami...) Show SMILES CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)=O)N=O Show InChI InChI=1S/C23H27N3O5/c1-24-22(28)20(26-31)9-4-2-3-5-10-21(27)25-19-8-6-7-18(15-19)16-11-13-17(14-12-16)23(29)30/h6-8,11-15,20H,2-5,9-10H2,1H3,(H,24,28)(H,25,27)(H,29,30)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC11 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assay				J Med Chem 54: 2165-82 (2011) Article DOI: 10.1021/jm101373a BindingDB Entry DOI: 10.7270/Q2CR5TNZ
					More data for this Ligand-Target Pair
Histone deacetylase 7 (Homo sapiens (Human))	BDBM50341852 (3'-(8-(Hydroxyimino)-9-(methylamino)-9-oxononanami...) Show SMILES CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)=O)N=O Show InChI InChI=1S/C23H27N3O5/c1-24-22(28)20(26-31)9-4-2-3-5-10-21(27)25-19-8-6-7-18(15-19)16-11-13-17(14-12-16)23(29)30/h6-8,11-15,20H,2-5,9-10H2,1H3,(H,24,28)(H,25,27)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC7 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assay				J Med Chem 54: 2165-82 (2011) Article DOI: 10.1021/jm101373a BindingDB Entry DOI: 10.7270/Q2CR5TNZ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50341852 (3'-(8-(Hydroxyimino)-9-(methylamino)-9-oxononanami...) Show SMILES CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)=O)N=O Show InChI InChI=1S/C23H27N3O5/c1-24-22(28)20(26-31)9-4-2-3-5-10-21(27)25-19-8-6-7-18(15-19)16-11-13-17(14-12-16)23(29)30/h6-8,11-15,20H,2-5,9-10H2,1H3,(H,24,28)(H,25,27)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC8 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assay				J Med Chem 54: 2165-82 (2011) Article DOI: 10.1021/jm101373a BindingDB Entry DOI: 10.7270/Q2CR5TNZ
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM50341852 (3'-(8-(Hydroxyimino)-9-(methylamino)-9-oxononanami...) Show SMILES CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)=O)N=O Show InChI InChI=1S/C23H27N3O5/c1-24-22(28)20(26-31)9-4-2-3-5-10-21(27)25-19-8-6-7-18(15-19)16-11-13-17(14-12-16)23(29)30/h6-8,11-15,20H,2-5,9-10H2,1H3,(H,24,28)(H,25,27)(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC9 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assay				J Med Chem 54: 2165-82 (2011) Article DOI: 10.1021/jm101373a BindingDB Entry DOI: 10.7270/Q2CR5TNZ
					More data for this Ligand-Target Pair
Histone deacetylase 10 (Homo sapiens (Human))	BDBM50341852 (3'-(8-(Hydroxyimino)-9-(methylamino)-9-oxononanami...) Show SMILES CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)=O)N=O Show InChI InChI=1S/C23H27N3O5/c1-24-22(28)20(26-31)9-4-2-3-5-10-21(27)25-19-8-6-7-18(15-19)16-11-13-17(14-12-16)23(29)30/h6-8,11-15,20H,2-5,9-10H2,1H3,(H,24,28)(H,25,27)(H,29,30)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC10 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assay				J Med Chem 54: 2165-82 (2011) Article DOI: 10.1021/jm101373a BindingDB Entry DOI: 10.7270/Q2CR5TNZ
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50341852 (3'-(8-(Hydroxyimino)-9-(methylamino)-9-oxononanami...) Show SMILES CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)=O)N=O Show InChI InChI=1S/C23H27N3O5/c1-24-22(28)20(26-31)9-4-2-3-5-10-21(27)25-19-8-6-7-18(15-19)16-11-13-17(14-12-16)23(29)30/h6-8,11-15,20H,2-5,9-10H2,1H3,(H,24,28)(H,25,27)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC6 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assay				J Med Chem 54: 2165-82 (2011) Article DOI: 10.1021/jm101373a BindingDB Entry DOI: 10.7270/Q2CR5TNZ
					More data for this Ligand-Target Pair