BDBM50342008 1-[2,5-Dideoxy-5-(4-carboxypiperidinyl)-beta-D-threopentofuranosyl]thymine::CHEMBL1765477
SMILES: Cc1cn([C@H]2C[C@@H](O)[C@@H](CN3CCC(CC3)C(O)=O)O2)c(=O)[nH]c1=O
InChI Key: InChIKey=LQRKISITQOPNHW-JHJVBQTASA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CAM-RNase A (Bison bison (American bison)) | BDBM50342008 (1-[2,5-Dideoxy-5-(4-carboxypiperidinyl)-beta-D-thr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.83E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Indian Institute of Technology Curated by ChEMBL | Assay Description Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as a substrate by Dixon plot analysis | Bioorg Med Chem 19: 2478-84 (2011) Article DOI: 10.1016/j.bmc.2010.08.059 BindingDB Entry DOI: 10.7270/Q2736R7B | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
CAM-RNase A (Bison bison (American bison)) | BDBM50342008 (1-[2,5-Dideoxy-5-(4-carboxypiperidinyl)-beta-D-thr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.29E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Indian Institute of Technology Curated by ChEMBL | Assay Description Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as a substrate by Lineweaver-Burk analysis | Bioorg Med Chem 19: 2478-84 (2011) Article DOI: 10.1016/j.bmc.2010.08.059 BindingDB Entry DOI: 10.7270/Q2736R7B | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |