BDBM50342052 1-(2-Chlorophenyl)-N-(4-cyanotetrahydro-2H-pyran-4-yl)-N,4-dimethyl-5-phenyl-1H-pyrazole-3-carboxamide::CHEMBL1765096

SMILES: CN(C(=O)c1nn(c(c1C)-c1ccccc1)-c1ccccc1Cl)C1(CCOCC1)C#N

InChI Key: InChIKey=YZIGARNHZQBJLB-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat))	BDBM50342052 (1-(2-Chlorophenyl)-N-(4-cyanotetrahydro-2H-pyran-4...) Show SMILES CN(C(=O)c1nn(c(c1C)-c1ccccc1)-c1ccccc1Cl)C1(CCOCC1)C#N Show InChI InChI=1S/C24H23ClN4O2/c1-17-21(23(30)28(2)24(16-26)12-14-31-15-13-24)27-29(20-11-7-6-10-19(20)25)22(17)18-8-4-3-5-9-18/h3-11H,12-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO receptor in rat kidney membranes				J Med Chem 54: 2961-70 (2011) Article DOI: 10.1021/jm2000536 BindingDB Entry DOI: 10.7270/Q2KS6SJS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50342052 (1-(2-Chlorophenyl)-N-(4-cyanotetrahydro-2H-pyran-4...) Show SMILES CN(C(=O)c1nn(c(c1C)-c1ccccc1)-c1ccccc1Cl)C1(CCOCC1)C#N Show InChI InChI=1S/C24H23ClN4O2/c1-17-21(23(30)28(2)24(16-26)12-14-31-15-13-24)27-29(20-11-7-6-10-19(20)25)22(17)18-8-4-3-5-9-18/h3-11H,12-15H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor				J Med Chem 54: 2961-70 (2011) Article DOI: 10.1021/jm2000536 BindingDB Entry DOI: 10.7270/Q2KS6SJS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50342052 (1-(2-Chlorophenyl)-N-(4-cyanotetrahydro-2H-pyran-4...) Show SMILES CN(C(=O)c1nn(c(c1C)-c1ccccc1)-c1ccccc1Cl)C1(CCOCC1)C#N Show InChI InChI=1S/C24H23ClN4O2/c1-17-21(23(30)28(2)24(16-26)12-14-31-15-13-24)27-29(20-11-7-6-10-19(20)25)22(17)18-8-4-3-5-9-18/h3-11H,12-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB2 receptor				J Med Chem 54: 2961-70 (2011) Article DOI: 10.1021/jm2000536 BindingDB Entry DOI: 10.7270/Q2KS6SJS
					More data for this Ligand-Target Pair