BDBM50342139 3-Imidazol-1-yl-2,2-dimethyl-3-(4-naphthalen-2-ylmethyl-phenyl)-propionicAcid Methyl Ester::CHEMBL1766015

SMILES: COC(=O)C(C)(C)C(c1ccc(Cc2ccc3ccccc3c2)cc1)n1ccnc1

InChI Key: InChIKey=RFDCXQLEVRXWOP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome CYP26A1 (Homo sapiens (Human))	BDBM50342139 (3-Imidazol-1-yl-2,2-dimethyl-3-(4-naphthalen-2-ylm...) Show SMILES COC(=O)C(C)(C)C(c1ccc(Cc2ccc3ccccc3c2)cc1)n1ccnc1 Show InChI InChI=1S/C26H26N2O2/c1-26(2,25(29)30-3)24(28-15-14-27-18-28)22-12-8-19(9-13-22)16-20-10-11-21-6-4-5-7-23(21)17-20/h4-15,17-18,24H,16H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation counting				J Med Chem 54: 2778-91 (2011) Article DOI: 10.1021/jm101583w BindingDB Entry DOI: 10.7270/Q2TT4R8J
					More data for this Ligand-Target Pair