BDBM50342532 2-(2-amino-3-(2-(2-chloro-4-hydroxyphenyl)thiazol-5-yl)propanamido)benzoic acid::CHEMBL1770172
SMILES: NC(Cc1cnc(s1)-c1ccc(O)cc1Cl)C(=O)Nc1ccccc1C(O)=O
InChI Key: InChIKey=XGHLSBKJJVJKFA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human)) | BDBM50342532 (2-(2-amino-3-(2-(2-chloro-4-hydroxyphenyl)thiazol-...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 930 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Agonist activity at human recombinant GPR109A receptor expressed in CHO-K1 cells after 60 mins by [35S]GTPgammaS binding assay | Bioorg Med Chem Lett 21: 2721-4 (2011) Article DOI: 10.1016/j.bmcl.2010.11.116 BindingDB Entry DOI: 10.7270/Q2N29X8C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human)) | BDBM50342532 (2-(2-amino-3-(2-(2-chloro-4-hydroxyphenyl)thiazol-...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]nicotinic acid from human GPR109A receptor | Bioorg Med Chem Lett 21: 2721-4 (2011) Article DOI: 10.1016/j.bmcl.2010.11.116 BindingDB Entry DOI: 10.7270/Q2N29X8C | |||||||||||
More data for this Ligand-Target Pair |