BDBM50342903 6-(benzo[d][1,3]dioxol-5-yl)-N-(2-(furan-2-yl)ethyl)quinazolin-4-amine::CHEMBL1357975

SMILES: C(Cc1ccco1)Nc1ncnc2ccc(cc12)-c1ccc2OCOc2c1

InChI Key: InChIKey=MQSQPFAQNYDQLL-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342903   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase CLK2 (Homo sapiens (Human))	BDBM50342903 (6-(benzo[d][1,3]dioxol-5-yl)-N-(2-(furan-2-yl)ethy...) Show SMILES C(Cc1ccco1)Nc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O3/c1-2-16(25-9-1)7-8-22-21-17-10-14(3-5-18(17)23-12-24-21)15-4-6-19-20(11-15)27-13-26-19/h1-6,9-12H,7-8,13H2,(H,22,23,24)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	801	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk2 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
CDC2-like kinase 3 (CLK3) (Homo sapiens (Human))	BDBM50342903 (6-(benzo[d][1,3]dioxol-5-yl)-N-(2-(furan-2-yl)ethy...) Show SMILES C(Cc1ccco1)Nc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O3/c1-2-16(25-9-1)7-8-22-21-17-10-14(3-5-18(17)23-12-24-21)15-4-6-19-20(11-15)27-13-26-19/h1-6,9-12H,7-8,13H2,(H,22,23,24)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk3 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-regulated kinases 1B (Homo sapiens (Human))	BDBM50342903 (6-(benzo[d][1,3]dioxol-5-yl)-N-(2-(furan-2-yl)ethy...) Show SMILES C(Cc1ccco1)Nc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O3/c1-2-16(25-9-1)7-8-22-21-17-10-14(3-5-18(17)23-12-24-21)15-4-6-19-20(11-15)27-13-26-19/h1-6,9-12H,7-8,13H2,(H,22,23,24)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Dyrk1B kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50342903 (6-(benzo[d][1,3]dioxol-5-yl)-N-(2-(furan-2-yl)ethy...) Show SMILES C(Cc1ccco1)Nc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O3/c1-2-16(25-9-1)7-8-22-21-17-10-14(3-5-18(17)23-12-24-21)15-4-6-19-20(11-15)27-13-26-19/h1-6,9-12H,7-8,13H2,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Dyrk1A kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual specificty protein kinase CLK1 (Homo sapiens (Human))	BDBM50342903 (6-(benzo[d][1,3]dioxol-5-yl)-N-(2-(furan-2-yl)ethy...) Show SMILES C(Cc1ccco1)Nc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O3/c1-2-16(25-9-1)7-8-22-21-17-10-14(3-5-18(17)23-12-24-21)15-4-6-19-20(11-15)27-13-26-19/h1-6,9-12H,7-8,13H2,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk1 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK4 (Homo sapiens (Human))	BDBM50342903 (6-(benzo[d][1,3]dioxol-5-yl)-N-(2-(furan-2-yl)ethy...) Show SMILES C(Cc1ccco1)Nc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O3/c1-2-16(25-9-1)7-8-22-21-17-10-14(3-5-18(17)23-12-24-21)15-4-6-19-20(11-15)27-13-26-19/h1-6,9-12H,7-8,13H2,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair