Found 2 hits for monomerid = 50342950 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human)) | BDBM50342950
((2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)...)Show SMILES CNc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c2ccc(cc2)-n2cccn2)c(s1)C1CC1 |r| Show InChI InChI=1S/C26H32N6O4S/c1-15(16-8-10-18(11-9-16)32-14-4-12-28-32)29-24(35)21(33)22(34)25(36)31-13-3-5-19(31)20-23(17-6-7-17)37-26(27-2)30-20/h4,8-12,14-15,17,19,21-22,33-34H,3,5-7,13H2,1-2H3,(H,27,30)(H,29,35)/t15-,19-,21-,22-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of TACE |
Bioorg Med Chem Lett 21: 3172-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.002 BindingDB Entry DOI: 10.7270/Q28P60T1 |
More data for this Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human)) | BDBM50342950
((2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)...)Show SMILES CNc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c2ccc(cc2)-n2cccn2)c(s1)C1CC1 |r| Show InChI InChI=1S/C26H32N6O4S/c1-15(16-8-10-18(11-9-16)32-14-4-12-28-32)29-24(35)21(33)22(34)25(36)31-13-3-5-19(31)20-23(17-6-7-17)37-26(27-2)30-20/h4,8-12,14-15,17,19,21-22,33-34H,3,5-7,13H2,1-2H3,(H,27,30)(H,29,35)/t15-,19-,21-,22-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of TACE by cell based assay |
Bioorg Med Chem Lett 21: 3172-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.002 BindingDB Entry DOI: 10.7270/Q28P60T1 |
More data for this Ligand-Target Pair | |