Found 4 hits for monomerid = 50343062 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50343062
(CHEMBL1770709 | N-hydroxy-4-(4-(4-oxo-4-(4-(triflu...)Show SMILES ONC(=O)C1(CCOCC1)S(=O)(=O)c1ccc(OCCCC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C23H25F3N2O8S/c24-23(25,26)36-18-5-3-16(4-6-18)27-20(29)2-1-13-35-17-7-9-19(10-8-17)37(32,33)22(21(30)28-31)11-14-34-15-12-22/h3-10,31H,1-2,11-15H2,(H,27,29)(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human MMP9 |
Bioorg Med Chem Lett 21: 2823-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.095
BindingDB Entry DOI: 10.7270/Q2CF9QD0 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50343062
(CHEMBL1770709 | N-hydroxy-4-(4-(4-oxo-4-(4-(triflu...)Show SMILES ONC(=O)C1(CCOCC1)S(=O)(=O)c1ccc(OCCCC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C23H25F3N2O8S/c24-23(25,26)36-18-5-3-16(4-6-18)27-20(29)2-1-13-35-17-7-9-19(10-8-17)37(32,33)22(21(30)28-31)11-14-34-15-12-22/h3-10,31H,1-2,11-15H2,(H,27,29)(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human MMP13 |
Bioorg Med Chem Lett 21: 2823-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.095
BindingDB Entry DOI: 10.7270/Q2CF9QD0 |
More data for this
Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50343062
(CHEMBL1770709 | N-hydroxy-4-(4-(4-oxo-4-(4-(triflu...)Show SMILES ONC(=O)C1(CCOCC1)S(=O)(=O)c1ccc(OCCCC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C23H25F3N2O8S/c24-23(25,26)36-18-5-3-16(4-6-18)27-20(29)2-1-13-35-17-7-9-19(10-8-17)37(32,33)22(21(30)28-31)11-14-34-15-12-22/h3-10,31H,1-2,11-15H2,(H,27,29)(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human MMP8 |
Bioorg Med Chem Lett 21: 2823-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.095
BindingDB Entry DOI: 10.7270/Q2CF9QD0 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50343062
(CHEMBL1770709 | N-hydroxy-4-(4-(4-oxo-4-(4-(triflu...)Show SMILES ONC(=O)C1(CCOCC1)S(=O)(=O)c1ccc(OCCCC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C23H25F3N2O8S/c24-23(25,26)36-18-5-3-16(4-6-18)27-20(29)2-1-13-35-17-7-9-19(10-8-17)37(32,33)22(21(30)28-31)11-14-34-15-12-22/h3-10,31H,1-2,11-15H2,(H,27,29)(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human MMP2 |
Bioorg Med Chem Lett 21: 2823-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.095
BindingDB Entry DOI: 10.7270/Q2CF9QD0 |
More data for this
Ligand-Target Pair | |
Search and Browse
