Found 8 hits for monomerid = 50343085 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Collagenase 3
(Homo sapiens (Human)) | BDBM50343085
(1-ethyl-N-hydroxy-4-(4-(3-(3-(4-(trifluoromethoxy)...)Show SMILES CCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCCCc2nc(no2)-c2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C26H29F3N4O7S/c1-2-33-15-13-25(14-16-33,24(34)31-35)41(36,37)21-11-9-19(10-12-21)38-17-3-4-22-30-23(32-40-22)18-5-7-20(8-6-18)39-26(27,28)29/h5-12,35H,2-4,13-17H2,1H3,(H,31,34) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human MMP-13 |
Bioorg Med Chem Lett 21: 2820-2 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.099
BindingDB Entry DOI: 10.7270/Q2416XCK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50343085
(1-ethyl-N-hydroxy-4-(4-(3-(3-(4-(trifluoromethoxy)...)Show SMILES CCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCCCc2nc(no2)-c2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C26H29F3N4O7S/c1-2-33-15-13-25(14-16-33,24(34)31-35)41(36,37)21-11-9-19(10-12-21)38-17-3-4-22-30-23(32-40-22)18-5-7-20(8-6-18)39-26(27,28)29/h5-12,35H,2-4,13-17H2,1H3,(H,31,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human MMP-3 |
Bioorg Med Chem Lett 21: 2820-2 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.099
BindingDB Entry DOI: 10.7270/Q2416XCK |
More data for this
Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50343085
(1-ethyl-N-hydroxy-4-(4-(3-(3-(4-(trifluoromethoxy)...)Show SMILES CCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCCCc2nc(no2)-c2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C26H29F3N4O7S/c1-2-33-15-13-25(14-16-33,24(34)31-35)41(36,37)21-11-9-19(10-12-21)38-17-3-4-22-30-23(32-40-22)18-5-7-20(8-6-18)39-26(27,28)29/h5-12,35H,2-4,13-17H2,1H3,(H,31,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human MMP-8 |
Bioorg Med Chem Lett 21: 2820-2 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.099
BindingDB Entry DOI: 10.7270/Q2416XCK |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50343085
(1-ethyl-N-hydroxy-4-(4-(3-(3-(4-(trifluoromethoxy)...)Show SMILES CCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCCCc2nc(no2)-c2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C26H29F3N4O7S/c1-2-33-15-13-25(14-16-33,24(34)31-35)41(36,37)21-11-9-19(10-12-21)38-17-3-4-22-30-23(32-40-22)18-5-7-20(8-6-18)39-26(27,28)29/h5-12,35H,2-4,13-17H2,1H3,(H,31,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human MMP-9 |
Bioorg Med Chem Lett 21: 2820-2 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.099
BindingDB Entry DOI: 10.7270/Q2416XCK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50343085
(1-ethyl-N-hydroxy-4-(4-(3-(3-(4-(trifluoromethoxy)...)Show SMILES CCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCCCc2nc(no2)-c2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C26H29F3N4O7S/c1-2-33-15-13-25(14-16-33,24(34)31-35)41(36,37)21-11-9-19(10-12-21)38-17-3-4-22-30-23(32-40-22)18-5-7-20(8-6-18)39-26(27,28)29/h5-12,35H,2-4,13-17H2,1H3,(H,31,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human MMP-2 |
Bioorg Med Chem Lett 21: 2820-2 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.099
BindingDB Entry DOI: 10.7270/Q2416XCK |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50343085
(1-ethyl-N-hydroxy-4-(4-(3-(3-(4-(trifluoromethoxy)...)Show SMILES CCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCCCc2nc(no2)-c2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C26H29F3N4O7S/c1-2-33-15-13-25(14-16-33,24(34)31-35)41(36,37)21-11-9-19(10-12-21)38-17-3-4-22-30-23(32-40-22)18-5-7-20(8-6-18)39-26(27,28)29/h5-12,35H,2-4,13-17H2,1H3,(H,31,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human MMP-7 |
Bioorg Med Chem Lett 21: 2820-2 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.099
BindingDB Entry DOI: 10.7270/Q2416XCK |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-14
(Homo sapiens (Human)) | BDBM50343085
(1-ethyl-N-hydroxy-4-(4-(3-(3-(4-(trifluoromethoxy)...)Show SMILES CCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCCCc2nc(no2)-c2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C26H29F3N4O7S/c1-2-33-15-13-25(14-16-33,24(34)31-35)41(36,37)21-11-9-19(10-12-21)38-17-3-4-22-30-23(32-40-22)18-5-7-20(8-6-18)39-26(27,28)29/h5-12,35H,2-4,13-17H2,1H3,(H,31,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human MMP-14 |
Bioorg Med Chem Lett 21: 2820-2 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.099
BindingDB Entry DOI: 10.7270/Q2416XCK |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50343085
(1-ethyl-N-hydroxy-4-(4-(3-(3-(4-(trifluoromethoxy)...)Show SMILES CCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCCCc2nc(no2)-c2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C26H29F3N4O7S/c1-2-33-15-13-25(14-16-33,24(34)31-35)41(36,37)21-11-9-19(10-12-21)38-17-3-4-22-30-23(32-40-22)18-5-7-20(8-6-18)39-26(27,28)29/h5-12,35H,2-4,13-17H2,1H3,(H,31,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human MMP-1 |
Bioorg Med Chem Lett 21: 2820-2 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.099
BindingDB Entry DOI: 10.7270/Q2416XCK |
More data for this
Ligand-Target Pair | |
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