BDBM50343116 4-(2-ethylphenyl)-N-(3-ethylphenyl)-2-(pyridin-3-yl)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxamide::CHEMBL1771251

SMILES: CCc1cccc(NC(=O)N2CCc3nc(nc(c3C2)-c2ccccc2CC)-c2cccnc2)c1

InChI Key: InChIKey=KXMSYCOPFVTPLB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2Y purinoceptor 14 (Mus musculus)	BDBM50343116 (4-(2-ethylphenyl)-N-(3-ethylphenyl)-2-(pyridin-3-y...) Show SMILES CCc1cccc(NC(=O)N2CCc3nc(nc(c3C2)-c2ccccc2CC)-c2cccnc2)c1 Show InChI InChI=1S/C29H29N5O/c1-3-20-9-7-12-23(17-20)31-29(35)34-16-14-26-25(19-34)27(24-13-6-5-10-21(24)4-2)33-28(32-26)22-11-8-15-30-18-22/h5-13,15,17-18H,3-4,14,16,19H2,1-2H3,(H,31,35)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...				Bioorg Med Chem Lett 21: 2832-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.084 BindingDB Entry DOI: 10.7270/Q20865N7
					More data for this Ligand-Target Pair