BDBM50343120 4-(2,6-dimethylphenyl)-N-(3-ethylphenyl)-2-(pyridin-3-yl)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxamide::CHEMBL1771439

SMILES: CCc1cccc(NC(=O)N2CCc3nc(nc(c3C2)-c2c(C)cccc2C)-c2cccnc2)c1

InChI Key: InChIKey=JLMAYMOTYPBMJB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343120   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2Y purinoceptor 14 (Mus musculus)	BDBM50343120 (4-(2,6-dimethylphenyl)-N-(3-ethylphenyl)-2-(pyridi...) Show SMILES CCc1cccc(NC(=O)N2CCc3nc(nc(c3C2)-c2c(C)cccc2C)-c2cccnc2)c1 |(10.19,-.57,;8.86,.2,;7.53,-.58,;7.53,-2.13,;6.2,-2.9,;4.86,-2.13,;4.87,-.59,;3.53,.18,;2.2,-.59,;2.2,-2.13,;.87,.18,;.86,1.73,;-.48,2.51,;-1.81,1.73,;-3.15,2.49,;-4.47,1.72,;-4.47,.18,;-3.14,-.59,;-1.81,.18,;-.48,-.59,;-3.14,-2.12,;-4.47,-2.89,;-5.81,-2.12,;-4.47,-4.43,;-3.13,-5.2,;-1.8,-4.42,;-1.81,-2.89,;-.47,-2.11,;-5.8,2.49,;-7.14,1.71,;-8.47,2.48,;-8.47,4.03,;-7.14,4.8,;-5.81,4.04,;6.19,.19,)| Show InChI InChI=1S/C29H29N5O/c1-4-21-10-6-12-23(16-21)31-29(35)34-15-13-25-24(18-34)27(26-19(2)8-5-9-20(26)3)33-28(32-25)22-11-7-14-30-17-22/h5-12,14,16-17H,4,13,15,18H2,1-3H3,(H,31,35)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...				Bioorg Med Chem Lett 21: 2832-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.084 BindingDB Entry DOI: 10.7270/Q20865N7
					More data for this Ligand-Target Pair