BDBM50343143 2-oxo-N-(6,7,8,9-tetrahydrodibenzo[b,d]furan-2-yl)-1,2-dihydrobenzo[cd]indole-6-sulfonamide::CHEMBL1773169

SMILES: O=C1Nc2ccc(c3cccc1c23)S(=O)(=O)Nc1ccc2oc3CCCCc3c2c1

InChI Key: InChIKey=HTSUWUDWBPZBQC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Tyrosine Phosphatase PTPB (Mycobacterium tuberculosis)	BDBM50343143 (2-oxo-N-(6,7,8,9-tetrahydrodibenzo[b,d]furan-2-yl)...) Show SMILES O=C1Nc2ccc(c3cccc1c23)S(=O)(=O)Nc1ccc2oc3CCCCc3c2c1 Show InChI InChI=1S/C23H18N2O4S/c26-23-16-6-3-5-15-21(11-9-18(24-23)22(15)16)30(27,28)25-13-8-10-20-17(12-13)14-4-1-2-7-19(14)29-20/h3,5-6,8-12,25H,1-2,4,7H2,(H,24,26)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB				ACS Med Chem Lett 1: 355-359 (2010) Article DOI: 10.1021/ml1001135 BindingDB Entry DOI: 10.7270/Q26M37TG
					More data for this Ligand-Target Pair
Protein Tyrosine Phosphatase PTPB (Mycobacterium tuberculosis)	BDBM50343143 (2-oxo-N-(6,7,8,9-tetrahydrodibenzo[b,d]furan-2-yl)...) Show SMILES O=C1Nc2ccc(c3cccc1c23)S(=O)(=O)Nc1ccc2oc3CCCCc3c2c1 Show InChI InChI=1S/C23H18N2O4S/c26-23-16-6-3-5-15-21(11-9-18(24-23)22(15)16)30(27,28)25-13-8-10-20-17(12-13)14-4-1-2-7-19(14)29-20/h3,5-6,8-12,25H,1-2,4,7H2,(H,24,26)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB preincubated with compound for 30 mins before pNPP substrate addition by micropl...				ACS Med Chem Lett 1: 355-359 (2010) Article DOI: 10.1021/ml1001135 BindingDB Entry DOI: 10.7270/Q26M37TG
					More data for this Ligand-Target Pair