BDBM50343144 CHEMBL1773170::N-(3-chloro-4-hydroxynaphthalen-1-yl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide
SMILES: Oc1c(Cl)cc(NS(=O)(=O)c2ccc3NC(=O)c4cccc2c34)c2ccccc12
InChI Key: InChIKey=PWVPVPJXCKMXDA-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein Tyrosine Phosphatase PTPB (Mycobacterium tuberculosis) | BDBM50343144 (CHEMBL1773170 | N-(3-chloro-4-hydroxynaphthalen-1-...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB | ACS Med Chem Lett 1: 355-359 (2010) Article DOI: 10.1021/ml1001135 BindingDB Entry DOI: 10.7270/Q26M37TG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein Tyrosine Phosphatase PTPB (Mycobacterium tuberculosis) | BDBM50343144 (CHEMBL1773170 | N-(3-chloro-4-hydroxynaphthalen-1-...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB preincubated with compound for 30 mins before pNPP substrate addition by micropl... | ACS Med Chem Lett 1: 355-359 (2010) Article DOI: 10.1021/ml1001135 BindingDB Entry DOI: 10.7270/Q26M37TG | |||||||||||
More data for this Ligand-Target Pair |