BDBM50343259 7-(5-(4-(2,3-dichlorophenyl)piperazin-1-yl)pentyl)-3,4-dihydro-1,8-naphthyridin-2(1H)-one::CHEMBL1774062

SMILES: Clc1cccc(N2CCN(CCCCCc3ccc4CCC(=O)Nc4n3)CC2)c1Cl

InChI Key: InChIKey=PPTRNJJUIFECMW-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343259   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50343259 (7-(5-(4-(2,3-dichlorophenyl)piperazin-1-yl)pentyl)...) Show SMILES Clc1cccc(N2CCN(CCCCCc3ccc4CCC(=O)Nc4n3)CC2)c1Cl Show InChI InChI=1S/C23H28Cl2N4O/c24-19-6-4-7-20(22(19)25)29-15-13-28(14-16-29)12-3-1-2-5-18-10-8-17-9-11-21(30)27-23(17)26-18/h4,6-8,10H,1-3,5,9,11-16H2,(H,26,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human 5HT2A receptor				Bioorg Med Chem Lett 21: 2621-5 (2011) Article DOI: 10.1016/j.bmcl.2011.01.059 BindingDB Entry DOI: 10.7270/Q29K4BJ3
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50343259 (7-(5-(4-(2,3-dichlorophenyl)piperazin-1-yl)pentyl)...) Show SMILES Clc1cccc(N2CCN(CCCCCc3ccc4CCC(=O)Nc4n3)CC2)c1Cl Show InChI InChI=1S/C23H28Cl2N4O/c24-19-6-4-7-20(22(19)25)29-15-13-28(14-16-29)12-3-1-2-5-18-10-8-17-9-11-21(30)27-23(17)26-18/h4,6-8,10H,1-3,5,9,11-16H2,(H,26,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 2621-5 (2011) Article DOI: 10.1016/j.bmcl.2011.01.059 BindingDB Entry DOI: 10.7270/Q29K4BJ3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50343259 (7-(5-(4-(2,3-dichlorophenyl)piperazin-1-yl)pentyl)...) Show SMILES Clc1cccc(N2CCN(CCCCCc3ccc4CCC(=O)Nc4n3)CC2)c1Cl Show InChI InChI=1S/C23H28Cl2N4O/c24-19-6-4-7-20(22(19)25)29-15-13-28(14-16-29)12-3-1-2-5-18-10-8-17-9-11-21(30)27-23(17)26-18/h4,6-8,10H,1-3,5,9,11-16H2,(H,26,27,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	11.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cells				Bioorg Med Chem Lett 21: 2621-5 (2011) Article DOI: 10.1016/j.bmcl.2011.01.059 BindingDB Entry DOI: 10.7270/Q29K4BJ3
					More data for this Ligand-Target Pair