BDBM50343363 2-(2-amino-6-methylpyrimidin-4-yl)-3-chlorophenol::CHEMBL1774834

SMILES: Cc1cc(nc(N)n1)-c1c(O)cccc1Cl

InChI Key: InChIKey=BHWXLIHTXJZXLV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM50343363 (2-(2-amino-6-methylpyrimidin-4-yl)-3-chlorophenol ...) Show SMILES Cc1cc(nc(N)n1)-c1c(O)cccc1Cl Show InChI InChI=1S/C11H10ClN3O/c1-6-5-8(15-11(13)14-6)10-7(12)3-2-4-9(10)16/h2-5,16H,1H3,(H2,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...				J Med Chem 54: 3368-85 (2011) Article DOI: 10.1021/jm200128m BindingDB Entry DOI: 10.7270/Q2Z320M5
					More data for this Ligand-Target Pair