BDBM50343417 1-[2-Chloro-2-(4-chlorophenyl)ethyl]-N-(pyridin-4-ylmethyl)-1Hpyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1775046

SMILES: ClC(Cn1ncc2c(NCc3ccncc3)ncnc12)c1ccc(Cl)cc1

InChI Key: InChIKey=LHXWTIIFWARQLP-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50343417 (1-[2-Chloro-2-(4-chlorophenyl)ethyl]-N-(pyridin-4-...) Show SMILES ClC(Cn1ncc2c(NCc3ccncc3)ncnc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H16Cl2N6/c20-15-3-1-14(2-4-15)17(21)11-27-19-16(10-26-27)18(24-12-25-19)23-9-13-5-7-22-8-6-13/h1-8,10,12,17H,9,11H2,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant c-Abl by filter-binding assay				J Med Chem 54: 2610-26 (2011) Article DOI: 10.1021/jm1012819 BindingDB Entry DOI: 10.7270/Q28K79F5
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50343417 (1-[2-Chloro-2-(4-chlorophenyl)ethyl]-N-(pyridin-4-...) Show SMILES ClC(Cn1ncc2c(NCc3ccncc3)ncnc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H16Cl2N6/c20-15-3-1-14(2-4-15)17(21)11-27-19-16(10-26-27)18(24-12-25-19)23-9-13-5-7-22-8-6-13/h1-8,10,12,17H,9,11H2,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant c-Src by filter-binding assay				J Med Chem 54: 2610-26 (2011) Article DOI: 10.1021/jm1012819 BindingDB Entry DOI: 10.7270/Q28K79F5
					More data for this Ligand-Target Pair