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SMILES: Cn1c(cc(=O)n(C)c1=O)N1CCCN(CC\C=C2\c3ccccc3CCc3ccc(cc23)C(O)=O)CC1

InChI Key: InChIKey=SPYSLLTXIWIQNL-MWYAZZEHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343580   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))		BDBM50343580
PNG
((5Z)-5-{3-[4-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetra...)
Show SMILES Cn1c(cc(=O)n(C)c1=O)N1CCCN(CC\C=C2\c3ccccc3CCc3ccc(cc23)C(O)=O)CC1
Show InChI InChI=1S/C30H34N4O4/c1-31-27(20-28(35)32(2)30(31)38)34-16-6-15-33(17-18-34)14-5-9-25-24-8-4-3-7-21(24)10-11-22-12-13-23(29(36)37)19-26(22)25/h3-4,7-9,12-13,19-20H,5-6,10-11,14-18H2,1-2H3,(H,36,37)/b25-9-
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Article
PubMed
n/an/a 153n/an/an/an/an/an/a



Dainippon Sumitomo Pharma. Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting

Bioorg Med Chem 19: 3005-21 (2011)


Article DOI: 10.1016/j.bmc.2011.03.003
BindingDB Entry DOI: 10.7270/Q23T9HJM
More data for this
Ligand-Target Pair