BDBM50343885 4-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-7-(4-(trifluoromethyl)phenyl)-2-naphthoic acid::CHEMBL1774900
SMILES: OC(c1ccc(cc1)-c1cc(cc2cc(ccc12)-c1ccc(cc1)C(F)(F)F)C(O)=O)C(F)(F)F
InChI Key: InChIKey=UTXQUOONYQJDAF-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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P2Y purinoceptor 14 (Mus musculus) | BDBM50343885 (4-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-7-(4-...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair |