BDBM50343970 CHEMBL1779603::rac-(2R,3R)-2,3-dihydroxy-N-((5-((2-methyl-1H-benzo[d]imidazol-1-yl)methyl)thiophen-2-yl)methyl)-4-oxo-4-(2-(pyridin-3-yl)pyrrolidin-1-yl)butanamide

SMILES: Cc1nc2ccccc2n1Cc1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccnc2)s1

InChI Key: InChIKey=VLPUVRSYGZOYBD-QJBRXVLMSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50343970 (CHEMBL1779603 | rac-(2R,3R)-2,3-dihydroxy-N-((5-((...) Show SMILES Cc1nc2ccccc2n1Cc1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccnc2)s1 |r| Show InChI InChI=1S/C27H29N5O4S/c1-17-30-21-7-2-3-8-23(21)32(17)16-20-11-10-19(37-20)15-29-26(35)24(33)25(34)27(36)31-13-5-9-22(31)18-6-4-12-28-14-18/h2-4,6-8,10-12,14,22,24-25,33-34H,5,9,13,15-16H2,1H3,(H,29,35)/t22?,24-,25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of TACE				Bioorg Med Chem Lett 20: 4812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.104 BindingDB Entry DOI: 10.7270/Q2GX4BWK
					More data for this Ligand-Target Pair