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BDBM50343996 2,4-dimethylpyrido[1,2-a]pyrimidin-5-ium-3-olate::CHEMBL1779949

SMILES: Cc1nc2cccc[n+]2c(C)c1[O-]

InChI Key: InChIKey=KDTJYDLSCGZZLD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343996   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cystic fibrosis transmembrane conductance regulator


(Homo sapiens (Human))
BDBM50343996
PNG
(2,4-dimethylpyrido[1,2-a]pyrimidin-5-ium-3-olate |...)
Show SMILES Cc1nc2cccc[n+]2c(C)c1[O-]
Show InChI InChI=1S/C10H10N2O/c1-7-10(13)8(2)12-6-4-3-5-9(12)11-7/h3-6H,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 5n/an/an/an/an/an/a



University Joseph Fourier-Grenoble 1/CNRS

Curated by ChEMBL


Assay Description
Inhibition of wild type CFTR expressed in CHO cells by [125I]iodide efflux assay


Eur J Med Chem 46: 1935-41 (2011)


Article DOI: 10.1016/j.ejmech.2011.02.037
BindingDB Entry DOI: 10.7270/Q23R0T6R
More data for this
Ligand-Target Pair