BDBM50344029 CHEMBL1780084::trans-(3R,5R)-5-ethyl-1-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((tetrahydro-2H-pyran-4-yl)methyl)piperidine-3-carboxamide

SMILES: CC[C@@H]1C[C@H](CN(Cc2nc(oc2C)-c2ccccc2)C1)C(=O)NCC1CCOCC1

InChI Key: InChIKey=TZTZUIQXHKAHBD-DENIHFKCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 8 (Homo sapiens (Human))	BDBM50344029 (CHEMBL1780084 | trans-(3R,5R)-5-ethyl-1-((5-methyl...) Show SMILES CC[C@@H]1C[C@H](CN(Cc2nc(oc2C)-c2ccccc2)C1)C(=O)NCC1CCOCC1 |r| Show InChI InChI=1S/C25H35N3O3/c1-3-19-13-22(24(29)26-14-20-9-11-30-12-10-20)16-28(15-19)17-23-18(2)31-25(27-23)21-7-5-4-6-8-21/h4-8,19-20,22H,3,9-17H2,1-2H3,(H,26,29)/t19-,22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE8B				Bioorg Med Chem Lett 21: 3095-8 (2011) Article DOI: 10.1016/j.bmcl.2011.03.022 BindingDB Entry DOI: 10.7270/Q20002F8
					More data for this Ligand-Target Pair