BDBM50344113 CHEMBL1777971::N-((R)-6-(morpholinomethyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-2-((R)-3-oxo-1-tosylpiperazin-2-yl)acetamide

SMILES: Cc1ccc(cc1)S(=O)(=O)N1CCNC(=O)[C@H]1CC(=O)N[C@@H]1CCCc2cc(CN3CCOCC3)ccc12

InChI Key: InChIKey=JOXQFASOZWSFHR-CLJLJLNGSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344113   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50344113 (CHEMBL1777971 | N-((R)-6-(morpholinomethyl)-1,2,3,...) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCNC(=O)[C@H]1CC(=O)N[C@@H]1CCCc2cc(CN3CCOCC3)ccc12 |r| Show InChI InChI=1S/C28H36N4O5S/c1-20-5-8-23(9-6-20)38(35,36)32-12-11-29-28(34)26(32)18-27(33)30-25-4-2-3-22-17-21(7-10-24(22)25)19-31-13-15-37-16-14-31/h5-10,17,25-26H,2-4,11-16,18-19H2,1H3,(H,29,34)(H,30,33)/t25-,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor				Bioorg Med Chem Lett 21: 3384-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.115 BindingDB Entry DOI: 10.7270/Q2FX79R6
					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50344113 (CHEMBL1777971 | N-((R)-6-(morpholinomethyl)-1,2,3,...) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCNC(=O)[C@H]1CC(=O)N[C@@H]1CCCc2cc(CN3CCOCC3)ccc12 |r| Show InChI InChI=1S/C28H36N4O5S/c1-20-5-8-23(9-6-20)38(35,36)32-12-11-29-28(34)26(32)18-27(33)30-25-4-2-3-22-17-21(7-10-24(22)25)19-31-13-15-37-16-14-31/h5-10,17,25-26H,2-4,11-16,18-19H2,1H3,(H,29,34)(H,30,33)/t25-,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor expressed in CHO cells assessed as inhibition of agonist-induced calcium efflux by aquerin based ...				Bioorg Med Chem Lett 21: 3384-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.115 BindingDB Entry DOI: 10.7270/Q2FX79R6
					More data for this Ligand-Target Pair