BDBM50344170 2-((7R)-7-(N-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid::CHEMBL1778508

SMILES: CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)C(=O)C1CCCc2ccccc12

InChI Key: InChIKey=NCHMLYQLIKIWRI-ITUIMRKVSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50344170 (2-((7R)-7-(N-methyl-1,2,3,4-tetrahydronaphthalene-...) Show SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)C(=O)C1CCCc2ccccc12 |r| Show InChI InChI=1S/C26H28N2O3/c1-27(26(31)21-11-6-8-17-7-2-3-9-19(17)21)18-13-14-24-22(15-25(29)30)20-10-4-5-12-23(20)28(24)16-18/h2-5,7,9-10,12,18,21H,6,8,11,13-16H2,1H3,(H,29,30)/t18-,21?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Curated by ChEMBL					Assay Description Binding affinity to human CRTH2 receptor expressed in HEK293-EBNA cells by radioligand competition binding assay				Bioorg Med Chem Lett 21: 3471-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.085 BindingDB Entry DOI: 10.7270/Q2T72HSR
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50344170 (2-((7R)-7-(N-methyl-1,2,3,4-tetrahydronaphthalene-...) Show SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)C(=O)C1CCCc2ccccc12 |r| Show InChI InChI=1S/C26H28N2O3/c1-27(26(31)21-11-6-8-17-7-2-3-9-19(17)21)18-13-14-24-22(15-25(29)30)20-10-4-5-12-23(20)28(24)16-18/h2-5,7,9-10,12,18,21H,6,8,11,13-16H2,1H3,(H,29,30)/t18-,21?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in HEK293-EBNA cells assessed as inhibition of forskolin-stimulated intracellular cAMP producti...				Bioorg Med Chem Lett 21: 3471-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.085 BindingDB Entry DOI: 10.7270/Q2T72HSR
					More data for this Ligand-Target Pair